Senior Research Associate (In Vivo)

Senior Research Associate (In Vivo)

Company Summary:
OncoPep Inc, is an early clinical-stage biotechnology company (Cambridge, MA) focused on developing immunotherapeutics (specifically peptide-based cancer vaccines and non-engineered T cells for the treatment of cancer). The Company’s lead drug candidate is PVX-410, an HLA-restricted, multi-peptide vaccine targeting tumor antigens overexpressed in hematologic and solid tumors. To date, PVX-410 has been evaluated in Phase 1 trials evaluating safety and immunogenicity in patients with Multiple Myeloma (MM) and Triple Negative Breast Cancer (TNBC) and is currently in a Phase 2 clinical trial for TNBC.

Position Description:
We are looking to expand our Research team by recruiting a Senior Research Associate to primarily work with in vivo tumor models and be responsible for validating the in vivo pharmacology and therapeutic pipeline developed by the company. We are seeking a candidate passionate about driving high-impact projects for our target discovery program. This candidate will be expected to perform routine in vivo pharmacology studies (including tumor growth kinetics, test tolerability, anti-tumor efficacy, biodistribution, pharmacokinetic, pharmacodynamic, and immunogenicity studies). They will work with others across teams and functions in a highly collaborative atmosphere. This role will require broad knowledge of current concepts in cancer immunology and associated areas.


  • MS in a scientific discipline with 2+ years relevant industry experience, or BS in a scientific discipline with 5+ years’ experience
  • A candidate who loves to create novel, and impactful therapeutic approaches and is excited to translate scientific discoveries into cancer therapies

Preferred Qualifications:

  • Experience culturing and maintaining human tumor cell lines and primary human cells, with best practices in tissue culture is important
  • Pharmacological agent administration via IM, IV, IP, and SC dosing routes
  • Implantation of cancer cell lines and tumor-derived material (SC and orthotopic)
  • Collection of serum/plasma/whole blood, tissues, primary tumor material and metastases
  • Mouse anesthesia/analgesia
  • Necropsy and tissue collection in rodents

What are we offering?

  • A dynamic, fun, and learning culture in an exciting field
  • Exposure to pioneering science and the full scope of the drug development process
  • Innovative thinking: speed of adopting new technologies, clear prioritization, and using analytics to accelerate agile development
  • A unique opportunity to help develop the platform and strategy of a burgeoning company and the evolution of a new research and discovery team
  • Mentorship from experienced industry leaders who are passionate about science and enabling mentees to achieve their potential and beyond

Work Environment: This is a fast-growing organization which requires independence, strong communication skills and transparency, flexibility, a hands-on attitude, and willingness to tackle multi-disciplinary challenges. Willingness and ability to travel domestically and internationally is required; it is anticipated that this will be 10 % of work time.

Physical Demands: The physical demands are representative of an office environment.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

OncoPep is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. OncoPep also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of applicable law.

To apply please send CV to –